产品货号:
Z10419
中文名称:
ACVR2B抗体
英文名称:
Anti-ACVR2B Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-ACVR2B Antibody |
指标别名 | ACTRIIB;ActR-IIB;MGC116908 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB |
基因名称 | ACVR2B |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human ACVR2B (431-466aa VVHKKMRPTIKDHWLKHPGLAQLCVTIEECWDHDAE),identical to the related mouse and rat sequences. |
实际分子量 | 55KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Activin receptor type-2B is a protein that in humans is encoded by the ACVR2B gene.Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins.Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors.These receptors are all transmembrane proteins,composed of a ligand-binding extracellular domain with cysteine-rich region,a transmembrane domain,and a cytoplasmic domain with predicted serine/threonine specificity.Type I receptors are essential for signaling;and type II receptors are required for binding ligands and for expression of type I receptors.Type I and II receptors form a stable complex after ligand binding,resulting in phosphorylation of type I receptors by type II receptors.Type II receptors are considered to be constitutively active kinases.This ACVR2B gene encodes activin A type IIB receptor,which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor. |
Uniprot ID | Q13705 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | activin A receptor type 2B |
蛋白名全称 | Activin receptor type-2B |
推荐稀释比 | Western blot(WB) 1:500~2000 |
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